[Coral-List] SCTLD cause

Paul Muir paularwen at gmail.com
Mon Aug 1 07:28:45 UTC 2022


Wow, so no Koch's postulates for this disease (ie ability to produce
disease symptoms in susceptible individuals following a small
inoculation with a purified disease agent? This is a pretty basic
requirement in pathology and pointless speculating on causes without this?
Ideally the disease agent is isolated and cultured to make the inoculum,
although this is occasionally not possible if the pathogen is tricky to
culture or loses its pathogenicity during culture. Even producing symptoms
using a 0.22um filtered crude tissue extract would be informative (ie viral
vs bacterial agent). Curious why this hasn't been done?
Ex marine microbiologist/pathologist talking- although very ex!

PAUL


On Mon, 1 Aug 2022 at 08:28, Kaufman, Leslie S via Coral-List <
coral-list at coral.aoml.noaa.gov> wrote:

> Remember folks- it is at least plausible that SCTLD is not a single
> pathogen (though several may be involved as triggers), but rather a
> dysbiosis, or microbiome dysfunction.  Essentially, a cnidarian UTI.
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